diff --git a/sstables/compress.cc b/sstables/compress.cc
index cda3a30be1..211be48caa 100644
--- a/sstables/compress.cc
+++ b/sstables/compress.cc
@@ -121,7 +121,11 @@ size_t compress_lz4(const char* input, size_t input_len,
     output[1] = (input_len >> 8) & 0xFF;
     output[2] = (input_len >> 16) & 0xFF;
     output[3] = (input_len >> 24) & 0xFF;
+#ifdef HAVE_LZ4_COMPRESS_DEFAULT
+    auto ret = LZ4_compress_default(input, output + 4, input_len, LZ4_compressBound(input_len));
+#else
     auto ret = LZ4_compress(input, output + 4, input_len);
+#endif
     if (ret == 0) {
         throw std::runtime_error("LZ4 compression failure: LZ4_compress() failed");
     }
diff --git a/transport/server.cc b/transport/server.cc
index 7158226fb7..2282ee9998 100644
--- a/transport/server.cc
+++ b/transport/server.cc
@@ -1504,7 +1504,11 @@ std::vector<char> cql_server::response::compress_lz4(const std::vector<char>& bo
     output[1] = (input_len >> 16) & 0xFF;
     output[2] = (input_len >> 8) & 0xFF;
     output[3] = input_len & 0xFF;
+#ifdef HAVE_LZ4_COMPRESS_DEFAULT
+    auto ret = LZ4_compress_default(input, output + 4, input_len, LZ4_compressBound(input_len));
+#else
     auto ret = LZ4_compress(input, output + 4, input_len);
+#endif
     if (ret == 0) {
         throw std::runtime_error("CQL frame LZ4 compression failure");
     }